Second Empire building viewed diagonally across intersection. Cranage Building contains businesses of A.B. Lyons, analytical chemist; A.B. Stevens, druggist; C. Rischert, confectioner; and Foster Bros. homeopathic pharmacy. Man in overcoat standing by entrance to Detroit Medical & Library Association. Horse-drawn vehicles on side street. Handwritten on albumen print mat back: "S.E. cor. Lafayette Ave & Shelby St., about 1881." Print was folded across image.
